Principal AI/ML Engineer – Digital Pathology – Remote

The Digital Biology team is the advanced technology group for Mayo Clinic Digital Pathology. We are looking for a Principal AI/ML Engineer to be a key engineering leader for our most ambitious platforms, from multimodal biological foundation models (pathology, -omics, imaging) to AI Virtual Cells, Tissues, and Organs. Guided by our scientific and clinical leadership, you will provide the senior, hands-on technical leadership required to turn complex concepts into tangible products. You will also mentor other engineers and ensure our shared infrastructure can redefine the future of diagnostics.

As a Principal AI/ML Engineer, you will lead the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
This role is instrumental in leading consultative services to departments and divisions, offering insights into complex business problems. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.

Providing strategic direction and technical leadership for AI Engineering initiatives.
Working with leadership team to define the AI roadmap and prioritize projects aligned with organizational objectives.
Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
Leading the collaboration with multidisciplinary teams, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
Leading the interpretation of data analysis to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications.
Leading consultative services to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications.
Establish rigorous evaluation methodologies and performance metrics to assess the effectiveness, usability, and impact of AI solutions in real-world healthcare settings.
Ensuring compliance with ethical guidelines, regulatory requirements, and data privacy standards in the development and deployment of AI solutions by the AI development team.
Overseeing the engineering of systems crucial for developing and deploying AI solutions.
Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
Defining and implementing best practices and standards for AI development and deployment methodologies, tools, and platforms.
Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. May have supervisory responsibilities.
Fostering a culture of collaboration, innovation, and knowledge sharing across the organization.
Supporting talent development initiatives, including training programs, technical workshops, and skill-building activities to enhance team capabilities.
Contributing to the development of new AI methods and technologies that can advance the state-of-the-art in healthcare AI.
Publishing and presenting the results of AI development and translation in peer-reviewed journals and conferences.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the “EOE is the Law”. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee’s Form I-9 to confirm work authorization.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.